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Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches


Clinical effectiveness research (CER) serves as the bridge between the development of innovative treatments and therapies and their productive application to improve human health. Building on efficacy and safety determinations necessary for regulatory approval, the results of these investigations guide the delivery of appropriate care to individual patients. As the complexity, number, and diversity of treatment options grow, the provision of clinical effectiveness information is increasingly essential for a safe and efficient healthcare system. Currently, the rapid expansion in scientific knowledge is inefficiently translated from scientific lab to clinical practice (Balas and Boren, 2000; McGlynn, 2003). Limited resources play a part in this problem. Of our nation’s more than $2 trillion investment in health care, an estimated less than 0.1 percent is devoted to evaluating the relative effectiveness of the various diagnostics, procedures, devices, pharmaceuticals, and other interventions in clinical practice (AcademyHealth, 2005; Moses et al., 2005).
978-0-309-11988-7
NONE
Healthcare Management
English
2010
1-443
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